Engineered Sumoylation-Deficient Prdx6 Mutant Protein-Loaded Nanoparticles Provide Increased Cellular Defense and Prevent Lens Opacity

Aberrant Sumoylation-mediated protein dysfunction is involved in a variety of oxidative and aging pathologies. We previously reported that Sumoylation-deficient Prdx6K<sup>(lysine)122/142R(Arginine)</sup> linked to the TAT-transduction domain gained stability and protective efficacy. In...

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Main Authors: Bhavana Chhunchha (Author), Eri Kubo (Author), Uday B. Kompella (Author), Dhirendra P. Singh (Author)
Format: Book
Published: MDPI AG, 2021-08-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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