Mequindox Induced Genotoxicity and Carcinogenicity in Mice

• मुख्य लेखकों: Qianying Liu (लेखक), Zhixin Lei (लेखक), Qin Wu (लेखक), Deyu Huang (लेखक), Shuyu Xie (लेखक), Xu Wang (लेखक), Yuanhu Pan (लेखक), Zonghui Yuan (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2018-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Mequindox (MEQ), acting as an inhibitor of deoxyribonucleic acid (DNA) synthesis, is a synthetic heterocyclic N-oxides. To investigate the potential carcinogenicity of MEQ, four groups of Kun-Ming (KM) mice (50 mice/sex/group) were fed with diets containing MEQ (0, 25, 55, and 110 mg/kg) for one and...