Mequindox Induced Genotoxicity and Carcinogenicity in Mice

• Päätekijät: Qianying Liu (Tekijä), Zhixin Lei (Tekijä), Qin Wu (Tekijä), Deyu Huang (Tekijä), Shuyu Xie (Tekijä), Xu Wang (Tekijä), Yuanhu Pan (Tekijä), Zonghui Yuan (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Frontiers Media S.A., 2018-04-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Mequindox (MEQ), acting as an inhibitor of deoxyribonucleic acid (DNA) synthesis, is a synthetic heterocyclic N-oxides. To investigate the potential carcinogenicity of MEQ, four groups of Kun-Ming (KM) mice (50 mice/sex/group) were fed with diets containing MEQ (0, 25, 55, and 110 mg/kg) for one and...