Bone Marrow-Derived Mesenchymal Stem Cells and γ-Secretase Inhibitor Treatments Suppress Amyloid-β25-35-Induced Cognitive Impairment in Rat Dams and Cortical Degeneration in Offspring

• Hoofdauteurs: Asmaa Gaber (Auteur), Ahlam M. Elbakry (Auteur), Rabab M. Aljarari (Auteur), Fatima A. Jaber (Auteur), Yasser A. Khadrawy (Auteur), Dina Sabry (Auteur), Rasha E. Abo-ELeneen (Auteur), Osama M. Ahmed (Auteur)
• Formaat: Boek
• Gepubliceerd in: Hindawi Limited, 2023-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Alzheimer's disease (AD) is the most frequent cause of age-related neurodegeneration and ensuing cognitive impairment. Progressive deposition of extracellular amyloid beta (Aβ) aggregates (plaques) and intracellular hyperphosphorylated Tau protein (p-Tau) are the core pathological markers of AD...