Bone Marrow-Derived Mesenchymal Stem Cells and γ-Secretase Inhibitor Treatments Suppress Amyloid-β25-35-Induced Cognitive Impairment in Rat Dams and Cortical Degeneration in Offspring

• मुख्य लेखकों: Asmaa Gaber (लेखक), Ahlam M. Elbakry (लेखक), Rabab M. Aljarari (लेखक), Fatima A. Jaber (लेखक), Yasser A. Khadrawy (लेखक), Dina Sabry (लेखक), Rasha E. Abo-ELeneen (लेखक), Osama M. Ahmed (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Hindawi Limited, 2023-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Alzheimer's disease (AD) is the most frequent cause of age-related neurodegeneration and ensuing cognitive impairment. Progressive deposition of extracellular amyloid beta (Aβ) aggregates (plaques) and intracellular hyperphosphorylated Tau protein (p-Tau) are the core pathological markers of AD...