High incidence of severe cyclosporine neurotoxicity in children affected by haemoglobinopaties undergoing myeloablative haematopoietic stem cell transplantation: early diagnosis and prompt intervention ameliorates neurological outcome

• Main Authors: Minicucci Fabio (Author), Vezzulli Paolo (Author), Baldoli Cristina (Author), Finizio Valentina (Author), Biral Erika (Author), Frugnoli Ilaria (Author), Chiesa Robert (Author), Biffi Alessandra (Author), Cappelli Barbara (Author), Noè Anna (Author), Fanelli Giovanna (Author), Fiori Rossana (Author), Ciceri Fabio (Author), Roncarolo Maria (Author), Marktel Sarah (Author)
• Format: Book
• Published: BMC, 2010-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Neurotoxicity is a recognized complication of cyclosporine A (CSA) treatment. The incidence of severe CSA-related neurological complications following hematopoietic stem cell transplantation (HSCT) is 4-11%.</p> <p>Method...