High incidence of severe cyclosporine neurotoxicity in children affected by haemoglobinopaties undergoing myeloablative haematopoietic stem cell transplantation: early diagnosis and prompt intervention ameliorates neurological outcome

• المؤلفون الرئيسيون: Minicucci Fabio (مؤلف), Vezzulli Paolo (مؤلف), Baldoli Cristina (مؤلف), Finizio Valentina (مؤلف), Biral Erika (مؤلف), Frugnoli Ilaria (مؤلف), Chiesa Robert (مؤلف), Biffi Alessandra (مؤلف), Cappelli Barbara (مؤلف), Noè Anna (مؤلف), Fanelli Giovanna (مؤلف), Fiori Rossana (مؤلف), Ciceri Fabio (مؤلف), Roncarolo Maria (مؤلف), Marktel Sarah (مؤلف)
• التنسيق: كتاب
• منشور في: BMC, 2010-02-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Neurotoxicity is a recognized complication of cyclosporine A (CSA) treatment. The incidence of severe CSA-related neurological complications following hematopoietic stem cell transplantation (HSCT) is 4-11%.</p> <p>Method...