Alternative splicing for tuneable expression of protein subunits at desired ratios

• मुख्य लेखकों: Christel Aebischer-Gumy (लेखक), Pierre Moretti (लेखक), Timothee Brunstein Laplace (लेखक), Jana Frank (लेखक), Ysaline Grand (लेखक), Farid Mosbaoui (लेखक), Emilie Hily (लेखक), Anna Galea (लेखक), Megane Peltret (लेखक), Carole Estoppey (लेखक), Daniel Ayoub (लेखक), Roberto Giovannini (लेखक), Martin Bertschinger (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

ABSTRACTThe controlled expression of two or more proteins at a defined and stable ratio remains a substantial challenge, particularly in the bi- and multispecific antibody field. Achieving an optimal ratio of protein subunits can facilitate the assembly of multimeric proteins with high efficiency an...