Homology modeling and docking studies of Plasmodium falciparum telomerase reverse transcriptase with berberine and some of its derivatives

• 主要な著者: Pratap Parida (著者), Samhita Kalita (著者), R. N. S. Yadav (著者), Brajesh Shankar (著者)
• フォーマット: 図書
• 出版事項: Bangladesh Pharmacological Society, 2014-02-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

The telomerase reverse transcriptase (TERT) sequence from Plasmodium falciparum provides valuable information for the design of specific anti-telomerase drugs. The present study deals with the interaction of pfTERT against berberine derivatives to derive novel analogues. Berberine intercalates DNA,...