Homology modeling and docking studies of Plasmodium falciparum telomerase reverse transcriptase with berberine and some of its derivatives

• मुख्य लेखकों: Pratap Parida (लेखक), Samhita Kalita (लेखक), R. N. S. Yadav (लेखक), Brajesh Shankar (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Bangladesh Pharmacological Society, 2014-02-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The telomerase reverse transcriptase (TERT) sequence from Plasmodium falciparum provides valuable information for the design of specific anti-telomerase drugs. The present study deals with the interaction of pfTERT against berberine derivatives to derive novel analogues. Berberine intercalates DNA,...