Homology modeling and docking studies of Plasmodium falciparum telomerase reverse transcriptase with berberine and some of its derivatives

• Main Authors: Pratap Parida (Author), Samhita Kalita (Author), R. N. S. Yadav (Author), Brajesh Shankar (Author)
• Formato: Libro
• Publicado: Bangladesh Pharmacological Society, 2014-02-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

The telomerase reverse transcriptase (TERT) sequence from Plasmodium falciparum provides valuable information for the design of specific anti-telomerase drugs. The present study deals with the interaction of pfTERT against berberine derivatives to derive novel analogues. Berberine intercalates DNA,...