Technical approaches for mouse models of human disease

• Asıl Yazarlar: Monica J. Justice (Yazar), Linda D. Siracusa (Yazar), A. Francis Stewart (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: The Company of Biologists, 2011-05-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

The mouse is the leading organism for disease research. A rich resource of genetic variation occurs naturally in inbred and special strains owing to spontaneous mutations. However, one can also obtain desired gene mutations by using the following processes: targeted mutations that eliminate function...