Umuhengerin Neuroprotective Effects in Streptozotocin-Induced Alzheimer's Disease Mouse Model via Targeting Nrf2 and NF-Kβ Signaling Cascades

• Главные авторы: Alaa Sirwi (Автор), Nesrine S. El Sayed (Автор), Hossam M. Abdallah (Автор), Sabrin R. M. Ibrahim (Автор), Gamal A. Mohamed (Автор), Ali M. El-Halawany (Автор), Martin K. Safo (Автор), Nora O. Abdel Rasheed (Автор)
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• Опубликовано: MDPI AG, 2021-12-01T00:00:00Z.
• Предметы: article
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Alzheimer's disease (AD) is the most common type of dementia and is characterized by advanced cognitive deterioration, deposition of Aβ (amyloid-beta), and the formation of neurofibrillary tangles. Administration of streptozotocin (STZ) via the intracerebroventricular (ICV) route is a reliable...