Effects of a spleen tyrosine kinase inhibitor on progression of the lupus nephritis in mice

• मुख्य लेखकों: Maki Kitai (लेखक), Noboru Fukuda (लेखक), Takahiro Ueno (लेखक), Morito Endo (लेखक), Takashi Maruyama (लेखक), Masanori Abe (लेखक), Kazuyoshi Okada (लेखक), Masayoshi Soma (लेखक), Koichi Matsumoto (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2017-05-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The Fc receptors (FcR) have pivotal roles in the pathogenesis of the autoimmune glomerulonephritis. We therefore investigated the effects of a Syk inhibitor on the progression of lupus nephritis and SH3 domain binding protein 2 and p38MAP kinase signalings in mice. NZB/W F1 mice, a model of lupus ne...