Selective histamine H2 receptor agonists alleviate blood-brain barrier disruption by promoting the expression of vascular protective factors following traumatic brain injury in mice

• Główni autorzy: Shotaro Michinaga (Autor), Kiyomi Sonoda (Autor), Naoki Inazuki (Autor), Manae Ezaki (Autor), Hiroki Awane (Autor), Kahori Shimizu (Autor), Shigeru Hishinuma (Autor), Hiroyuki Mizuguchi (Autor)
• Format: Książka
• Wydane: Elsevier, 2022-11-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Histamine is a major neurotransmitter and alleviates neuronal damage after ischemic injury via H2 receptors. Herein, we investigated the effects of H2 receptor agonists on the blood-brain barrier (BBB) disruption after traumatic brain injury (TBI). Male ddY mice were used to generate the TBI model,...