Selective histamine H2 receptor agonists alleviate blood-brain barrier disruption by promoting the expression of vascular protective factors following traumatic brain injury in mice

• Päätekijät: Shotaro Michinaga (Tekijä), Kiyomi Sonoda (Tekijä), Naoki Inazuki (Tekijä), Manae Ezaki (Tekijä), Hiroki Awane (Tekijä), Kahori Shimizu (Tekijä), Shigeru Hishinuma (Tekijä), Hiroyuki Mizuguchi (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Elsevier, 2022-11-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Histamine is a major neurotransmitter and alleviates neuronal damage after ischemic injury via H2 receptors. Herein, we investigated the effects of H2 receptor agonists on the blood-brain barrier (BBB) disruption after traumatic brain injury (TBI). Male ddY mice were used to generate the TBI model,...