Aryl Hydrocarbon Receptor-Dependent and -Independent Pathways Mediate Curcumin Anti-Aging Effects

• Главные авторы: Vanessa Brinkmann (Автор), Margherita Romeo (Автор), Lucie Larigot (Автор), Anne Hemmers (Автор), Lisa Tschage (Автор), Jennifer Kleinjohann (Автор), Alfonso Schiavi (Автор), Swantje Steinwachs (Автор), Charlotte Esser (Автор), Ralph Menzel (Автор), Sara Giani Tagliabue (Автор), Laura Bonati (Автор), Fiona Cox (Автор), Niloofar Ale-Agha (Автор), Philipp Jakobs (Автор), Joachim Altschmied (Автор), Judith Haendeler (Автор), Xavier Coumoul (Автор), Natascia Ventura (Автор)
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• Опубликовано: MDPI AG, 2022-03-01T00:00:00Z.
• Предметы: article
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The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor whose activity can be modulated by polyphenols, such as curcumin. AhR and curcumin have evolutionarily conserved effects on aging. Here, we investigated whether and how the AhR mediates the anti-aging effects of curcumin...