4β-Hydroxycholesterol Signals From the Liver to Regulate Peripheral Cholesterol Transporters

4β-Hydroxycholesterol Signals From the Liver to Regulate Peripheral Cholesterol Transporters

Activation of pregnane X receptor (PXR) elevates circulating 4β-hydroxycholesterol (4βHC), an agonist of liver X receptor (LXR). PXR may also regulate 25-hydroxycholesterol and 27-hydroxycholesterol. Our aim was to elucidate the roles of PXR and oxysterols in the regulation of cholesterol transporte...

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Main Authors: Tuire Salonurmi (Author), Heba Nabil (Author), Justiina Ronkainen (Author), Tuulia Hyötyläinen (Author), Heidi Hautajärvi (Author), Markku J. Savolainen (Author), Ari Tolonen (Author), Matej Orešič (Author), Päivi Känsäkoski (Author), Jaana Rysä (Author), Jukka Hakkola (Author), Janne Hukkanen (Author)
Format: Book
Published: Frontiers Media S.A., 2020-03-01T00:00:00Z.
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