4β-Hydroxycholesterol Signals From the Liver to Regulate Peripheral Cholesterol Transporters

• 主要な著者: Tuire Salonurmi (著者), Heba Nabil (著者), Justiina Ronkainen (著者), Tuulia Hyötyläinen (著者), Heidi Hautajärvi (著者), Markku J. Savolainen (著者), Ari Tolonen (著者), Matej Orešič (著者), Päivi Känsäkoski (著者), Jaana Rysä (著者), Jukka Hakkola (著者), Janne Hukkanen (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2020-03-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Activation of pregnane X receptor (PXR) elevates circulating 4β-hydroxycholesterol (4βHC), an agonist of liver X receptor (LXR). PXR may also regulate 25-hydroxycholesterol and 27-hydroxycholesterol. Our aim was to elucidate the roles of PXR and oxysterols in the regulation of cholesterol transporte...