In Vitro Evaluation of Aerosol Therapy with Pentamidine-Loaded Liposomes Coated with Chondroitin Sulfate or Heparin for the Treatment of Leishmaniasis

• Автори: Lucía Román-Álamo (Автор), Mohamad Allaw (Автор), Yunuen Avalos-Padilla (Автор), Maria Letizia Manca (Автор), Maria Manconi (Автор), Federica Fulgheri (Автор), Jorge Fernández-Lajo (Автор), Luis Rivas (Автор), José Antonio Vázquez (Автор), José Esteban Peris (Автор), Xavier Roca-Geronès (Автор), Srisupaph Poonlaphdecha (Автор), Maria Magdalena Alcover (Автор), Roser Fisa (Автор), Cristina Riera (Автор), Xavier Fernàndez-Busquets (Автор)
• Формат: Книга
• Опубліковано: MDPI AG, 2023-04-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

The second-line antileishmanial compound pentamidine is administered intramuscularly or, preferably, by intravenous infusion, with its use limited by severe adverse effects, including diabetes, severe hypoglycemia, myocarditis and renal toxicity. We sought to test the potential of phospholipid vesic...