Cover Image

Recombinant antigens expressed in Pichia pastoris for the diagnosis of sleeping sickness caused by Trypanosoma brucei gambiense.

Screening tests for gambiense sleeping sickness, such as the CATT/T. b. gambiense and a recently developed lateral flow tests, are hitherto based on native variant surface glycoproteins (VSGs), namely LiTat 1.3 and LiTat 1.5, purified from highly virulent trypanosome strains grown in rodents.We have...

Full description

Saved in:

Bibliographic Details
Main Authors:	Stijn Rogé (Author), Liesbeth Van Nieuwenhove (Author), Magali Meul (Author), Annick Heykers (Author), Annette Brouwer de Koning (Author), Nicolas Bebronne (Author), Yves Guisez (Author), Philippe Büscher (Author)
Format:	Book
Published:	Public Library of Science (PLoS), 2014-07-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Identification of peptide mimotopes of Trypanosoma brucei gambiense variant surface glycoproteins.
by: Liesbeth Carolien Van Nieuwenhove, et al.
Published: (2011)

Identification of mimotopes with diagnostic potential for Trypanosoma brucei gambiense variant surface glycoproteins using human antibody fractions.
by: Liesbeth Van Nieuwenhove, et al.
Published: (2012)

Expression of Trypanosoma brucei gambiense Antigens in Leishmania tarentolae. Potential for Use in Rapid Serodiagnostic Tests (RDTs).
by: Barrie Rooney, et al.
Published: (2015)

Using Pichia pastoris to produce recombinant glycerol kinase
by: Werner Damião Morhy Terrazas, et al.
Published: (2014)

Using Pichia pastoris to produce recombinant glycerol kinase
by: Werner Damião Morhy Terrazas, et al.
Published: (2014)

Bioprocess and downstream optimization of recombinant human growth hormone in Pichia pastoris
by: Saeed Azadi, et al.
Published: (2018)

Untreated human infections by Trypanosoma brucei gambiense are not 100% fatal.
by: Vincent Jamonneau, et al.
Published: (2012)

Development of insulin production in pichia pastoris GS115
by: Sasithorn Ngenprasertsiri
Published: (2013)

Aquaporin 2 mutations in Trypanosoma brucei gambiense field isolates correlate with decreased susceptibility to pentamidine and melarsoprol.
by: Fabrice E Graf, et al.
Published: (2013)

Prospective evaluation of a rapid diagnostic test for Trypanosoma brucei gambiense infection developed using recombinant antigens.
by: Crispin Lumbala, et al.
Published: (2018)

Heterologous expression of the antimyotoxic protein DM64 in Pichia pastoris.
by: Saulo Martins Vieira, et al.
Published: (2017)

A Primate APOL1 Variant That Kills Trypanosoma brucei gambiense.
by: Anneli Cooper, et al.
Published: (2016)

Neural Damage in Experimental Trypanosoma brucei gambiense Infection: The Suprachiasmatic Nucleus
by: Chiara Tesoriero, et al.
Published: (2018)

Optimization of Pichia pastoris Expression System for High-Level Production of Margatoxin
by: Muhammad Umair Naseem, et al.
Published: (2021)

Evaluation of the micro-CATT, CATT/Trypanosoma brucei gambiense, and LATEX/T. b. gambiense methods for serodiagnosis and surveillance of human African trypanosomiasis in West and Central Africa
by: Truc Philippe, et al.
Published: (2002)

Isolation of Trypanosoma brucei gambiense from cured and relapsed sleeping sickness patients and adaptation to laboratory mice.
by: Patient Pati Pyana, et al.
Published: (2011)

Optimized Expression and Purification of Humbug in Pichia pastoris and Its Monoclonal Antibody Preparation
by: Ting HUYAN, et al.
Published: (2015)

The genome sequence of Trypanosoma brucei gambiense, causative agent of chronic human african trypanosomiasis.
by: Andrew P Jackson, et al.
Published: (2010)

Trypanosoma brucei gambiense Infections in Mice Lead to Tropism to the Reproductive Organs, and Horizontal and Vertical Transmission.
by: Nicolas Biteau, et al.
Published: (2016)

Seeing beyond 2020: an economic evaluation of contemporary and emerging strategies for elimination of Trypanosoma brucei gambiense
by: C Simone Sutherland, PhD, et al.
Published: (2017)

NECT is next: implementing the new drug combination therapy for Trypanosoma brucei gambiense sleeping sickness.
by: Oliver Yun, et al.
Published: (2010)

Neopterin is a cerebrospinal fluid marker for treatment outcome evaluation in patients affected by Trypanosoma brucei gambiense sleeping sickness.
by: Natalia Tiberti, et al.
Published: (2013)

Melarsoprol sensitivity profile of Trypanosoma brucei gambiense isolates from cured and relapsed sleeping sickness patients from the Democratic Republic of the Congo.
by: Patient Pyana Pati, et al.
Published: (2014)

The effect of livestock density on Trypanosoma brucei gambiense and T. b. rhodesiense: A causal inference-based approach.
by: Julianne Meisner, et al.
Published: (2022)

Differences between Trypanosoma brucei gambiense groups 1 and 2 in their resistance to killing by trypanolytic factor 1.
by: Paul Capewell, et al.
Published: (2011)

Neural Damage in Experimental Trypanosoma brucei gambiense Infection: Hypothalamic Peptidergic Sleep and Wake-Regulatory Neurons
by: Claudia Laperchia, et al.
Published: (2018)

Genotypic status of the TbAT1/P2 adenosine transporter of Trypanosoma brucei gambiense isolates from Northwestern Uganda following melarsoprol withdrawal.
by: Anne J N Kazibwe, et al.
Published: (2009)

Sensitivity and Specificity of a Prototype Rapid Diagnostic Test for the Detection of Trypanosoma brucei gambiense Infection: A Multi-centric Prospective Study.
by: Sylvie Bisser, et al.
Published: (2016)

Murine Models for Trypanosoma brucei gambiense disease progression--from silent to chronic infections and early brain tropism.
by: Christiane Giroud, et al.
Published: (2009)

Stabilitas Ekspresi Kerangka Baca Terbuka Penyandi Interferon Alfa-2a pada Yeast Pichia pastoris
by: Try Kurniawan Mutaqien, -
Published: (2017)

Development and characterization of an enterovirus 71 (EV71) virus-like particles (VLPs) vaccine produced in Pichia pastoris
by: Zhijian Yang, et al.
Published: (2020)

Correction: Murine Models for Trypanosoma brucei gambiense Disease Progression-From Silent to Chronic Infections and Early Brain Tropism.
by: Christiane Giroud, et al.
Published: (2016)

Screening of Trypanosoma brucei gambiense in domestic livestock and tsetse flies from an insular endemic focus (Luba, Equatorial Guinea).
by: Carlos Cordon-Obras, et al.
Published: (2010)

UJI STABILITAS PROTEIN FUSI HUMAN SERUM ALBUMIN STRAIN SMD1168 YANG DIPRODUKSI DALAM YEAST Pichia pastoris
by: Naufan, Aldi Sujatmoko
Published: (2018)

Bioprocess optimization of interferon β-1-a in Pichia pastoris and its improved inhibitory effect against hepatocellular carcinoma cells
by: Nasim Moatamedi, et al.
Published: (2022)

Sensitivity and specificity of HAT Sero-K-SeT, a rapid diagnostic test for serodiagnosis of sleeping sickness caused by Trypanosoma brucei gambiense: a case-control study
by: Dr. Philippe Büscher, PhD, et al.
Published: (2014)

Pichia pastoris secreted peptides crossing the blood-brain barrier and DSIP fusion peptide efficacy in PCPA-induced insomnia mouse models
by: Xiaoxiao Mu, et al.
Published: (2024)

<i>Pichia pastoris</i> Mediated Digestion of Water-Soluble Polysaccharides from Cress Seed Mucilage Produces Potent Antidiabetic Oligosaccharides
by: Imdad Ullah Khan, et al.
Published: (2024)

Gambiense sleeping sickness: re-emerging and soon untreatable?
by: Simon Van Nieuwenhove
Published: (2000)

Gambiense sleeping sickness: re-emerging and soon untreatable?
by: Simon Van Nieuwenhove