Karanjin interferes with ABCB1, ABCC1, and ABCG2

• المؤلفون الرئيسيون: Martin Michaelis (مؤلف), Florian Rothweiler (مؤلف), Thomas Nerreter (مؤلف), Mohsen Sharifi (مؤلف), Taravat Ghafourian (مؤلف), Jindrich Cinatl (مؤلف)
• التنسيق: كتاب
• منشور في: Frontiers Media S.A., 2014-03-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

PURPOSE: The prominent ATP-binding cassette (ABC) transporters ABCB1, ABCC1, and ABCG2 are involved in substance transport across physiological barriers and therefore in drug absorption, distribution, and elimination. They also mediate multi-drug resistance in cancer cells. Different flavonoids are...