Variations in dysfunction of sister chromatid cohesion in esco2 mutant zebrafish reflect the phenotypic diversity of Roberts syndrome

• Glavni autori: Stefanie M. Percival (Autor), Holly R. Thomas (Autor), Adam Amsterdam (Autor), Andrew J. Carroll (Autor), Jacqueline A. Lees (Autor), H. Joseph Yost (Autor), John M. Parant (Autor)
• Format: Knjiga
• Izdano: The Company of Biologists, 2015-08-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Mutations in ESCO2, one of two establishment of cohesion factors necessary for proper sister chromatid cohesion (SCC), cause a spectrum of developmental defects in the autosomal-recessive disorder Roberts syndrome (RBS), warranting in vivo analysis of the consequence of cohesion dysfunction. Through...