Variations in dysfunction of sister chromatid cohesion in esco2 mutant zebrafish reflect the phenotypic diversity of Roberts syndrome

• Autori principali: Stefanie M. Percival (Autore), Holly R. Thomas (Autore), Adam Amsterdam (Autore), Andrew J. Carroll (Autore), Jacqueline A. Lees (Autore), H. Joseph Yost (Autore), John M. Parant (Autore)
• Natura: Libro
• Pubblicazione: The Company of Biologists, 2015-08-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Mutations in ESCO2, one of two establishment of cohesion factors necessary for proper sister chromatid cohesion (SCC), cause a spectrum of developmental defects in the autosomal-recessive disorder Roberts syndrome (RBS), warranting in vivo analysis of the consequence of cohesion dysfunction. Through...