Multivalent design of the monoclonal SynO2 antibody improves binding strength to soluble α-Synuclein aggregates
ABSTRACTSoluble aggregates are reported to be the most neurotoxic species of α-Synuclein (αSyn) in Parkinson's disease (PD) and hence are a promising target for diagnosis and treatment of PD. However, the predominantly intracellular location of αSyn limits its accessibility, especially for anti...
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Taylor & Francis Group,
2023-12-01T00:00:00Z.
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