Stability indicating HPLC and spectrophotometric methods for the determination of bupropion hydrochloride in the presence of its alkaline degradates and related impurity

• Main Authors: Samah S. Abbas (Author), Mohamed R. Elghobashy (Author), Rafeek F. Shokry (Author), Lories I. Bebawy (Author)
• פורמט: ספר
• יצא לאור: Faculty of Pharmacy, Cairo University, 2012-06-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Four sensitive and selective stability-indicating methods for the determination of bupropion hydrochloride in the presence of its alkaline degradates, related impurity, 3-chlorobenzoic acid, and in its pharmaceutical formulation were developed. Method A is an isocratic reversed phase HPLC, good sepa...