Stability indicating HPLC and spectrophotometric methods for the determination of bupropion hydrochloride in the presence of its alkaline degradates and related impurity

• Autors principals: Samah S. Abbas (Autor), Mohamed R. Elghobashy (Autor), Rafeek F. Shokry (Autor), Lories I. Bebawy (Autor)
• Format: Llibre
• Publicat: Faculty of Pharmacy, Cairo University, 2012-06-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Four sensitive and selective stability-indicating methods for the determination of bupropion hydrochloride in the presence of its alkaline degradates, related impurity, 3-chlorobenzoic acid, and in its pharmaceutical formulation were developed. Method A is an isocratic reversed phase HPLC, good sepa...