Liver Injury with Nintedanib: A Pharmacovigilance-Pharmacokinetic Appraisal

• Main Authors: Emanuel Raschi (Author), Michele Fusaroli (Author), Milo Gatti (Author), Paolo Caraceni (Author), Elisabetta Poluzzi (Author), Fabrizio De Ponti (Author)
• 格式: 图书
• 出版: MDPI AG, 2022-05-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Drug-induced liver injury (DILI) with nintedanib has emerged as an adverse event of special interest in premarketing clinical trials. We characterized DILI with nintedanib in the real world and explored the underlying pharmacological basis. First, we assessed serious hepatic events reported to the F...