Liver Injury with Nintedanib: A Pharmacovigilance-Pharmacokinetic Appraisal

• المؤلفون الرئيسيون: Emanuel Raschi (مؤلف), Michele Fusaroli (مؤلف), Milo Gatti (مؤلف), Paolo Caraceni (مؤلف), Elisabetta Poluzzi (مؤلف), Fabrizio De Ponti (مؤلف)
• التنسيق: كتاب
• منشور في: MDPI AG, 2022-05-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Drug-induced liver injury (DILI) with nintedanib has emerged as an adverse event of special interest in premarketing clinical trials. We characterized DILI with nintedanib in the real world and explored the underlying pharmacological basis. First, we assessed serious hepatic events reported to the F...