Inhibitory Effect of Luteolin on Spike S1 Glycoprotein-Induced Inflammation in THP-1 Cells via the ER Stress-Inducing Calcium/CHOP/MAPK Pathway

• Главные авторы: Sonthaya Umsumarng (Автор), Sivamoke Dissook (Автор), Punnida Arjsri (Автор), Kamonwan Srisawad (Автор), Pilaiporn Thippraphan (Автор), Apiwat Sangphukieo (Автор), Patcharawadee Thongkumkoon (Автор), Pornngarm Dejkriengkraikul (Автор)
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• Опубликовано: MDPI AG, 2024-10-01T00:00:00Z.
• Предметы: article
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Background/Objectives: The global SARS-CoV-2 outbreak has escalated into a critical public health emergency, with the spike glycoprotein S1 subunit of SARS-CoV-2 (spike-S1) linked to inflammation in lung tissue and immune cells. Luteolin, a flavone with anti-inflammatory properties, shows promise, b...