Morphing Natural Product Platensimycin via Heck, Sonogashira, and One-Pot Sonogashira/Cycloaddition Reactions to Produce Antibiotics with In Vivo Activity

Type II fatty acid synthases are promising drug targets against major bacterial pathogens. Platensimycin (PTM) is a potent inhibitor against <i>β</i>-ketoacyl-[acyl carrier protein] synthase II (FabF) and <i>β</i>-ketoacyl-[acyl carrier protein] synthase I (FabB), while the p...

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Main Authors: Youchao Deng (Author), Yuling Li (Author), Zhongqing Wen (Author), Claudia H. Ruiz (Author), Xiang Weng (Author), Michael D. Cameron (Author), Yanwen Duan (Author), Yong Huang (Author)
Format: Book
Published: MDPI AG, 2022-03-01T00:00:00Z.
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3rd Floor Main Library

Holdings details from 3rd Floor Main Library
Call Number: A1234.567
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