Upregulation of expression of the chemokine receptor CCR5 by hydrogen peroxide in human monocytes

• 主要な著者: Geneviève Lehoux (著者), Christian Le Gouill (著者), Jana Stankova (著者), Marek Rola-pleszczynski (著者)
• フォーマット: 図書
• 出版事項: Hindawi Limited, 2003-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

The objective of this study was to test the hypothesis that an oxidative stress can serve as a signal to regulate the expression of CCR5. When human monocytes were exposed to graded concentration of hydrogen peroxide (H2O2), CCR5 mRNA levels increased maximally at 4 h of exposure to 200 μM of H2O2 a...