Short-course, oral flubendazole does not mediate significant efficacy against Onchocerca adult male worms or Brugia microfilariae in murine infection models.
The Onchocerca ochengi adult implant and Brugia malayi microfilariemic Severe-Combined Immunodeficient (SCID) mouse models are validated screens to measure macrofilaricidal and microfilaricidal activities of candidate onchocerciasis drugs. The purpose of this study was to assess whether 5 daily sub-...
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Main Authors: | , , , , , , , , , , , , , , , , , , , , , |
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Format: | Book |
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Public Library of Science (PLoS),
2019-01-01T00:00:00Z.
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