Short-course, oral flubendazole does not mediate significant efficacy against Onchocerca adult male worms or Brugia microfilariae in murine infection models.

• Asıl Yazarlar: Hanna T Sjoberg (Yazar), Nicolas Pionnier (Yazar), Ghaith Aljayyoussi (Yazar), Haelly M Metuge (Yazar), Abdel J Njouendou (Yazar), Valerine C Chunda (Yazar), Fanny F Fombad (Yazar), Dizzle B Tayong (Yazar), Narcisse V T Gandjui (Yazar), Desmond N Akumtoh (Yazar), Patrick W N Chounna (Yazar), Bertrand L Ndzeshang (Yazar), Sophie Lachaud (Yazar), Fetene Tekle (Yazar), Ludo Quirynen (Yazar), Marc Engelen (Yazar), Benny Baeten (Yazar), Andrew Steven (Yazar), Stephen A Ward (Yazar), Mark J Taylor (Yazar), Samuel Wanji (Yazar), Joseph D Turner (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Public Library of Science (PLoS), 2019-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

The Onchocerca ochengi adult implant and Brugia malayi microfilariemic Severe-Combined Immunodeficient (SCID) mouse models are validated screens to measure macrofilaricidal and microfilaricidal activities of candidate onchocerciasis drugs. The purpose of this study was to assess whether 5 daily sub-...