Positive/retained SDHB immunostaining in renal cell carcinomas associated to germline SDHB-deficiency: case report

Abstract Background According to WHO, succinate dehydrogenase (SDH)-deficient renal cell carcinoma is characterized by negative immunostaining for SDHB, which remains positive in non-tumor tissue despite germline mutations in the SDHB gene. We now report a patient with a SDHB mutation, c.166_170del...

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Main Authors: Marina Ugarte-Camara (Author), Raul Fernandez-Prado (Author), Isabel Lorda (Author), Gabriela Rossello (Author), Carmen Gonzalez-Enguita (Author), Pablo Cannata-Ortiz (Author), Alberto Ortiz (Author)
Format: Book
Published: BMC, 2019-05-01T00:00:00Z.
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