Eluxadoline-Loaded Eudragit Nanoparticles for Irritable Bowel Syndrome with Diarrhea: Formulation, Optimization Using Box-Behnken Design, and Anti-Diarrheal Activity

• मुख्य लेखकों: Md. Khalid Anwer (लेखक), Mohammed Muqtader Ahmed (लेखक), Mohammed F. Aldawsari (लेखक), Muzaffar Iqbal (लेखक), Gamal A. Soliman (लेखक), Ibrahim A. Aljuffali (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2023-05-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Eluxadoline (ELD), a recently approved drug, exhibits potential therapeutic effects in the management and treatment of IBS-D. However, its applications have been limited due to poor aqueous solubility, leading to a low dissolution rate and oral bioavailability. The current study's goals are to...