Eluxadoline-Loaded Eudragit Nanoparticles for Irritable Bowel Syndrome with Diarrhea: Formulation, Optimization Using Box-Behnken Design, and Anti-Diarrheal Activity

• Päätekijät: Md. Khalid Anwer (Tekijä), Mohammed Muqtader Ahmed (Tekijä), Mohammed F. Aldawsari (Tekijä), Muzaffar Iqbal (Tekijä), Gamal A. Soliman (Tekijä), Ibrahim A. Aljuffali (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: MDPI AG, 2023-05-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Eluxadoline (ELD), a recently approved drug, exhibits potential therapeutic effects in the management and treatment of IBS-D. However, its applications have been limited due to poor aqueous solubility, leading to a low dissolution rate and oral bioavailability. The current study's goals are to...