Eluxadoline-Loaded Eudragit Nanoparticles for Irritable Bowel Syndrome with Diarrhea: Formulation, Optimization Using Box-Behnken Design, and Anti-Diarrheal Activity

• Asıl Yazarlar: Md. Khalid Anwer (Yazar), Mohammed Muqtader Ahmed (Yazar), Mohammed F. Aldawsari (Yazar), Muzaffar Iqbal (Yazar), Gamal A. Soliman (Yazar), Ibrahim A. Aljuffali (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2023-05-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Eluxadoline (ELD), a recently approved drug, exhibits potential therapeutic effects in the management and treatment of IBS-D. However, its applications have been limited due to poor aqueous solubility, leading to a low dissolution rate and oral bioavailability. The current study's goals are to...