Eluxadoline-Loaded Eudragit Nanoparticles for Irritable Bowel Syndrome with Diarrhea: Formulation, Optimization Using Box-Behnken Design, and Anti-Diarrheal Activity

• Auteurs principaux: Md. Khalid Anwer (Auteur), Mohammed Muqtader Ahmed (Auteur), Mohammed F. Aldawsari (Auteur), Muzaffar Iqbal (Auteur), Gamal A. Soliman (Auteur), Ibrahim A. Aljuffali (Auteur)
• Format: Livre
• Publié: MDPI AG, 2023-05-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Eluxadoline (ELD), a recently approved drug, exhibits potential therapeutic effects in the management and treatment of IBS-D. However, its applications have been limited due to poor aqueous solubility, leading to a low dissolution rate and oral bioavailability. The current study's goals are to...