The EGF Receptor and HER2 Participate in TNF-α-Dependent MAPK Activation and IL-8 Secretion in Intestinal Epithelial Cells

TNF-α activates multiple mitogen-activated protein kinase (MAPK) cascades in intestinal epithelial cells (IECs) leading to the secretion of interleukin 8 (IL-8), a neutrophil chemoattractant and an angiogenic factor with tumor promoting properties. As the epidermal growth factor receptor (EGFR) is a...

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Bibliographic Details
Main Authors: Humberto B. Jijon (Author), Andre Buret (Author), Christina L. Hirota (Author), Morley D. Hollenberg (Author), Paul L. Beck (Author)
Format: Book
Published: Hindawi Limited, 2012-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
Copy 1 Available