Liquid chromatography-mass spectrometry for simultaneous determination of spironolactone and canrenone in plasma samples

• Asıl Yazarlar: Ricardo Ferreira-Nunes (Yazar), Edson Aliel Teixeira de Almeida (Yazar), Marcilio Cunha-Filho (Yazar), Tais Gratieri (Yazar), Guilherme Martins Gelfuso (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Universidade de São Paulo, 2023-04-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Abstract In our study, we aimed to validate a method based on liquid chromatography-mass spectrometry (LC-MS) to quantify spironolactone (SPI) and its active metabolite canrenone (CAN) simultaneously in plasma samples to support in vivo experiments. Compounds were separated by using a C18 column wit...