Morc2a p.S87L mutant mice develop peripheral and central neuropathies associated with neuronal DNA damage and apoptosis

The microrchidia (MORC)-family CW-type zinc finger 2 (MORC2) gene is related to DNA repair, adipogenesis and epigenetic silencing via the human silencing hub (HUSH) complex. MORC2 missense mutation is known to cause peripheral neuropathy of Charcot-Marie-Tooth disease type 2 Z (CMT2Z). However, ther...

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Main Authors: Geon Seong Lee (Author), Geon Kwak (Author), Ji Hyun Bae (Author), Jeong Pil Han (Author), Soo Hyun Nam (Author), Jeong Hyeon Lee (Author), Sumin Song (Author), Gap-Don Kim (Author), Tae Sub Park (Author), Yang Kyu Choi (Author), Byung-Ok Choi (Author), Su Cheong Yeom (Author)
Format: Book
Published: The Company of Biologists, 2021-10-01T00:00:00Z.
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