Morc2a p.S87L mutant mice develop peripheral and central neuropathies associated with neuronal DNA damage and apoptosis

• Asıl Yazarlar: Geon Seong Lee (Yazar), Geon Kwak (Yazar), Ji Hyun Bae (Yazar), Jeong Pil Han (Yazar), Soo Hyun Nam (Yazar), Jeong Hyeon Lee (Yazar), Sumin Song (Yazar), Gap-Don Kim (Yazar), Tae Sub Park (Yazar), Yang Kyu Choi (Yazar), Byung-Ok Choi (Yazar), Su Cheong Yeom (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: The Company of Biologists, 2021-10-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

The microrchidia (MORC)-family CW-type zinc finger 2 (MORC2) gene is related to DNA repair, adipogenesis and epigenetic silencing via the human silencing hub (HUSH) complex. MORC2 missense mutation is known to cause peripheral neuropathy of Charcot-Marie-Tooth disease type 2 Z (CMT2Z). However, ther...