Suppression of virus specific immune responses by IL-10 in acute dengue infection.

• मुख्य लेखकों: Gathsaurie Neelika Malavige (लेखक), Chandima Jeewandara (लेखक), K M Luckmaal Alles (लेखक), Maryam Salimi (लेखक), Laksiri Gomes (लेखक), Achala Kamaladasa (लेखक), S D Jayaratne (लेखक), Graham Stuart Ogg (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Elevated IL-10 has been shown to be associated with severe dengue infection (DI). We proceeded to investigate the role of IL-10 in the pathogenesis of acute DI.Ex vivo and cultured IFNγ ELISpot assays for dengue virus (DENV) NS3 protein and non dengue viral proteins were carried out in 26 patients w...