SPECT Imaging with Tc-99m-Labeled HYNIC-FAPI-04 to Extend the Differential Time Window in Evaluating Tumor Fibrosis

• Principais autores: Xiu Luo (Autor), Zhe Zhang (Autor), Chao Cheng (Autor), Tao Wang (Autor), Danzhou Fang (Autor), Changjing Zuo (Autor), Gengbiao Yuan (Autor), Rou Li (Autor), Xiao Li (Autor)
• Formato: Livro
• Publicado em: MDPI AG, 2023-03-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

The so-far used Ga-68- or F-18-labelled tracers are of a relative short time window in differentiating tumor fibrosis. SPECT applicable imaging probe, ^99mTc-HYNIC-FAPI-04, was synthesized and evaluated in tumor cells and animal models of FAP-positive glioma and FAP-negative he...