Chapter 14 Coupled Enzyme Activity and Thermal Shift Screening of the Maybridge Rule of 3 Fragment Library Against Trypanosoma brucei Choline Kinase; A Genetically Validated Drug Target

In this study we interrogate 630 compounds of the Maybridge Rule of 3 Fragment Library for compounds that interact with, and inhibit TbCK. The Maybridge Rule of 3 Fragment Library is a small collection of quantifiable diverse, pharmacophoric rich, chemical entities that comply with the following cri...

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Bibliografiset tiedot
Päätekijä:	Denton, Helen (auth)
Muut tekijät:	Major, Louise L. (auth), Smith, Terry K. (auth)
Aineistotyyppi:	Elektroninen Kirjan osa
Kieli:	englanti
Julkaistu:	InTechOpen 2013
Aiheet:	Pharmacology pharmacology toxicology Assay Enzyme Molar concentration Protein Thermal shift assay Trypanosoma brucei
Linkit:	OAPEN Library: download the publication OAPEN Library: description of the publication
Tagit:	Lisää tagi Ei tageja, Lisää ensimmäinen tagi!

Chapter 14 Coupled Enzyme Activity and Thermal Shift Screening of the Maybridge Rule of 3 Fragment Library Against Trypanosoma brucei Choline Kinase; A Genetically Validated Drug T... Tekijä Denton, Helen

Julkaistu 2013

DOAB: download the publication
DOAB: description of the publication

Elektroninen Kirjan osa

Chapter 14 Coupled Enzyme Activity and Thermal Shift Screening of the Maybridge Rule of 3 Fragment Library Against Trypanosoma brucei Choline Kinase; A Genetically Validated Drug Target

Chapter 14 Coupled Enzyme Activity and Thermal Shift Screening of the Maybridge Rule of 3 Fragment Library Against Trypanosoma brucei Choline Kinase; A Genetically Validated Drug T... Tekijä Denton, Helen

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