Chapter 14 Coupled Enzyme Activity and Thermal Shift Screening of the Maybridge Rule of 3 Fragment Library Against Trypanosoma brucei Choline Kinase; A Genetically Validated Drug Target

In this study we interrogate 630 compounds of the Maybridge Rule of 3 Fragment Library for compounds that interact with, and inhibit TbCK. The Maybridge Rule of 3 Fragment Library is a small collection of quantifiable diverse, pharmacophoric rich, chemical entities that comply with the following cri...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
1. Verfasser: Denton, Helen (auth)
Weitere Verfasser: Major, Louise L. (auth), Smith, Terry K. (auth)
Format: Elektronisch Buchkapitel
Sprache:Englisch
Veröffentlicht: InTechOpen 2013
Schlagworte:
Online-Zugang:OAPEN Library: download the publication
OAPEN Library: description of the publication
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!