Chapter 13 Targeting Tumor Perfusion and Oxygenation Modulates Hypoxia and Cancer Sensitivity to Radiotherapy and Systemic Therapies

Hypoxia, a partial pressure of oxygen (pO2) below physiological needs, is a limiting factor affecting the efficiency of radiotherapy. Indeed, the reaction of reactive oxygen species (ROS, produced by water radiolysis) with DNA is readily reversible unless oxygen stabilizes the DNA lesion. While no...

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Detalles Bibliográficos
Autor Principal: Jordan, Bénédicte F. (auth)
Outros autores: Sonveaux, Pierre (auth)
Formato: Electrónico Capítulo de libro
Idioma:inglés
Publicado: InTechOpen 2011
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Acceso en liña:OAPEN Library: download the publication
OAPEN Library: description of the publication
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