Anti-VEGF Therapy Induces Proteinuria through Endothelial Disorganization Leading to Nephrin Decrease in Podocytes

• Váldodahkkit: Marianne Terrasse (Dahkki), Florence Jouan (Dahkki), Thibault Dolley-Hitze (Dahkki), Yannick Arlot-Bonnemains (Dahkki), Marc-Antoine (Dahkki), Nathalie Rioux-Leclercq (Dahkki), Nolwenn Lorcy (Dahkki), Cécile Vigneau (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: International Journal of Immunotherapy and Cancer Research - Peertechz Publications, 2015-10-28.
• Fáttát: Research Article
• Liŋkkat: Connect to this object online.

<p><strong>Background:</strong> VEGF is involved in cancer development by stimulating neo-angiogenesis and tumor proliferation. Anti-angiogenic therapies, especially tyrosine kinase inhibitors such as sunitinib, have significantly improved cancer prognosis. Nevertheless, renal side...