Anti-VEGF Therapy Induces Proteinuria through Endothelial Disorganization Leading to Nephrin Decrease in Podocytes

• Päätekijät: Marianne Terrasse (Tekijä), Florence Jouan (Tekijä), Thibault Dolley-Hitze (Tekijä), Yannick Arlot-Bonnemains (Tekijä), Marc-Antoine (Tekijä), Nathalie Rioux-Leclercq (Tekijä), Nolwenn Lorcy (Tekijä), Cécile Vigneau (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: International Journal of Immunotherapy and Cancer Research - Peertechz Publications, 2015-10-28.
• Aiheet: Research Article
• Linkit: Connect to this object online.

<p><strong>Background:</strong> VEGF is involved in cancer development by stimulating neo-angiogenesis and tumor proliferation. Anti-angiogenic therapies, especially tyrosine kinase inhibitors such as sunitinib, have significantly improved cancer prognosis. Nevertheless, renal side...