Editorial: Emerging talents in Frontiers in pharmacology: Gastrointestinal and hepatic pharmacology 2022 by Laura Grasa, Thomas Brzozowski, Marilia Seelaender

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Inflammation in Disease: Mechanism and Therapies by Gustavo Duarte Pimentel, Marília Seelaender, Fábio Santos Lira

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Metformin Mitigates Fibrosis and Glucose Intolerance Induced by Doxorubicin in Subcutaneous Adipose Tissue by Luana A. Biondo, Helena A. Batatinha, Camila O. Souza, Alexandre A. S. Teixeira, Loreana S. Silveira, Maria I. Alonso-Vale, Lila M. Oyama, Michele J. Alves, Marilia Seelaender, Marilia Seelaender, José C. R. Neto

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Cancer Cachexia and MicroRNAs by Rodolfo Gonzalez Camargo, Henrique Quintas Teixeira Ribeiro, Murilo Vieira Geraldo, Emídio Matos-Neto, Rodrigo Xavier Neves, Luiz Carlos Carnevali, Felipe Fedrizzi Donatto, Paulo S. M. Alcântara, José P. Ottoch, Marília Seelaender

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Impairment of aryl hydrocarbon receptor signalling promotes hepatic disorders in cancer cachexia by Adeline Dolly, Sarah A. Pötgens, Morgane M. Thibaut, Audrey M. Neyrinck, Gabriela S. deCastro, Chloé Galbert, Camille Lefevre, Elisabeth Wyart, Silvio P. Gomes, Daniela C. Gonçalves, Nicolas Lanthier, Pamela Baldin, Joshua R. Huot, Andrea Bonetto, Marília Seelaender, Nathalie M. Delzenne, Harry Sokol, Laure B. Bindels

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Peritumoural adipose tissue pro‐inflammatory cytokines are associated with tumoural growth factors in cancer cachexia patients by Nelson Inácio Pinto Neto, Ariene Soares de Pinho Murari, Lila Missae Oyama, José Pinhata Otoch, Paulo Sérgio Martins Alcântara, Flavio Tokeshi, Raquel Galvão Figuerêdo, Michele Joana Alves, Joanna Darck Carola Correia Lima, Emídio Marques de Matos‐Neto, Marilia Seelaender, Claudia Maria Oller do Nascimento

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Tumour‐derived transforming growth factor‐β signalling contributes to fibrosis in patients with cancer cachexia by Joanna D.C.C. Lima, Estefania Simoes, Gabriela deCastro, Mychel Raony P.T. Morais, Emidio M. deMatos‐Neto, Michele J. Alves, Nelson I. Pinto, Raquel G. Figueredo, Telma M.T. Zorn, Aloísio S. Felipe‐Silva, Flavio Tokeshi, José P. Otoch, Paulo Alcantara, Fernanda J. Cabral, Emer S. Ferro, Alessandro Laviano, Marilia Seelaender

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Cancer cachexia induces morphological and inflammatory changes in the intestinal mucosa by Raquel G.F. Costa, Paula L. Caro, Emídio M. deMatos‐Neto, Joanna D.C.C. Lima, Katrin Radloff, Michele J. Alves, Rodolfo G. Camargo, Ana Flávia M. Pessoa, Estefania Simoes, Patrícia Gama, Denise C. Cara, Aloísio S.F. daSilva, Welbert O. Pereira, Linda F. Maximiano, Paulo S.M. deAlcântara, José P. Otoch, Giorgio Trinchieri, Alessandro Laviano, Maurizio Muscaritoli, Marília Seelaender

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Cachexia causes time‐dependent activation of the inflammasome in the liver by Rodrigo Xavier dasNeves, Alex S. Yamashita, Daniela M.R. Riccardi, Julia Köhn‐Gaone, Rodolfo G. Camargo, Nelson I. Neto, Daniela Caetano, Silvio P. Gomes, Felipe H. Santos, Joanna D.C.C. Lima, Miguel L. Batista Jr, José Cesar Rosa‐Neto, Paulo Sérgio Martins De Alcântara, Linda F. Maximiano, José P. Otoch, Giorgio Trinchieri, Janina E.E. Tirnitz‐Parker, Marília Seelaender

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