Search Results - Matthew R Hassler

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  1. 1
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    2'-O-Methyl at 20-mer Guide Strand 3' Termini May Negatively Affect Target Silencing Activity of Fully Chemically Modified siRNA by Sarah M. Davis, Jacquelyn Sousa, Lorenc Vangjeli, Matthew R. Hassler, Dimas Echeverria, Emily Knox, Anton A. Turanov, Julia F. Alterman, Anastasia Khvorova

    Published 2020
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  2. 2
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    Docosahexaenoic Acid Conjugation Enhances Distribution and Safety of siRNA upon Local Administration in Mouse Brain by Mehran Nikan, Maire F Osborn, Andrew H Coles, Bruno MDC Godinho, Lauren M Hall, Reka A Haraszti, Matthew R Hassler, Dimas Echeverria, Neil Aronin, Anastasia Khvorova

    Published 2016
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  3. 3
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    Hydrophobically Modified siRNAs Silence Huntingtin mRNA in Primary Neurons and Mouse Brain by Julia F Alterman, Lauren M Hall, Andrew H Coles, Matthew R Hassler, Marie-Cecile Didiot, Kathryn Chase, Jasmin Abraham, Emily Sottosanti, Emily Johnson, Ellen Sapp, Maire F Osborn, Marian Difiglia, Neil Aronin, Anastasia Khvorova

    Published 2015
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  4. 4
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    PK-modifying anchors significantly alter clearance kinetics, tissue distribution, and efficacy of therapeutics siRNAs by Bruno M.D.C. Godinho, Emily G. Knox, Samuel Hildebrand, James W. Gilbert, Dimas Echeverria, Zachary Kennedy, Reka A. Haraszti, Chantal M. Ferguson, Andrew H. Coles, Annabelle Biscans, Jillian Caiazzi, Julia F. Alterman, Matthew R. Hassler, Anastasia Khvorova

    Published 2022
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