Search Results - Dimas Echeverria

Single-Stranded Phosphorothioated Regions Enhance Cellular Uptake of Cholesterol-Conjugated siRNA but Not Silencing Efficacy by Socheata Ly, Dimas Echeverria, Jacquelyn Sousa, Anastasia Khvorova

Connect to this object online.

Cell Type Impacts Accessibility of mRNA to Silencing by RNA Interference by Chantal M. Ferguson, Dimas Echeverria, Matthew Hassler, Socheata Ly, Anastasia Khvorova

Connect to this object online.

2'-O-Methyl at 20-mer Guide Strand 3' Termini May Negatively Affect Target Silencing Activity of Fully Chemically Modified siRNA by Sarah M. Davis, Jacquelyn Sousa, Lorenc Vangjeli, Matthew R. Hassler, Dimas Echeverria, Emily Knox, Anton A. Turanov, Julia F. Alterman, Anastasia Khvorova

Connect to this object online.

Docosahexaenoic Acid Conjugation Enhances Distribution and Safety of siRNA upon Local Administration in Mouse Brain by Mehran Nikan, Maire F Osborn, Andrew H Coles, Bruno MDC Godinho, Lauren M Hall, Reka A Haraszti, Matthew R Hassler, Dimas Echeverria, Neil Aronin, Anastasia Khvorova

Connect to this object online.

Single intravitreal administration of a tetravalent siRNA exhibits robust and efficient gene silencing in mouse and pig photoreceptors by Shun-Yun Cheng, Jillian Caiazzi, Annabelle Biscans, Julia F. Alterman, Dimas Echeverria, Nicholas McHugh, Matthew Hassler, Samson Jolly, Delaney Giguere, Joris Cipi, Anastasia Khvorova, Claudio Punzo

Connect to this object online.

Chemical optimization of siRNA for safe and efficient silencing of placental sFLT1 by Sarah M. Davis, Vignesh N. Hariharan, Agnes Lo, Anton A. Turanov, Dimas Echeverria, Jacquelyn Sousa, Nicholas McHugh, Annabelle Biscans, Julia F. Alterman, S. Ananth Karumanchi, Melissa J. Moore, Anastasia Khvorova

Connect to this object online.

Dendritic amphiphilic siRNA: Selective albumin binding, in vivo efficacy, and low toxicity by Hassan H. Fakih, Qi Tang, Ashley Summers, Minwook Shin, Julianna E. Buchwald, Rosemary Gagnon, Vignesh N. Hariharan, Dimas Echeverria, David A. Cooper, Jonathan K. Watts, Anastasia Khvorova, Hanadi F. Sleiman

Connect to this object online.

PK-modifying anchors significantly alter clearance kinetics, tissue distribution, and efficacy of therapeutics siRNAs by Bruno M.D.C. Godinho, Emily G. Knox, Samuel Hildebrand, James W. Gilbert, Dimas Echeverria, Zachary Kennedy, Reka A. Haraszti, Chantal M. Ferguson, Andrew H. Coles, Annabelle Biscans, Jillian Caiazzi, Julia F. Alterman, Matthew R. Hassler, Anastasia Khvorova

Connect to this object online.

Identification of selective and non-selective C9ORF72 targeting in vivo active siRNAs by James W. Gilbert, Zachary Kennedy, Bruno M.D.C. Godinho, Ashley Summers, Alexandra Weiss, Dimas Echeverria, Brianna Bramato, Nicholas McHugh, David Cooper, Ken Yamada, Matthew Hassler, Hélène Tran, Fen Biao Gao, Robert H. Brown, Jr, Anastasia Khvorova

Connect to this object online.