Frédéric Y. Bois

Frédéric Y. Bois Frédéric Yves Bois (born 1958) is a French biological scientist working in toxicology and bioinformatics. He is currently Senior Scientific Advisor at Simcyp, a Certara-owned company. Provided by Wikipedia
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  1. 1
    A Bayesian framework for virtual comparative trials and bioequivalence assessments

    A Bayesian framework for virtual comparative trials and bioequivalence assessments by Frederic Y. Bois, Céline Brochot

    Published 2024
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  2. 2
    Opening a debate on open‐source modeling tools: Pouring fuel on fire versus extinguishing the flare of a healthy debate

    Opening a debate on open‐source modeling tools: Pouring fuel on fire versus extinguishing the flare of a healthy debate by Amin Rostami‐Hodjegan, Frederic Y. Bois

    Published 2021
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  3. 3
    Applying a Global Sensitivity Analysis Workflow to Improve the Computational Efficiencies in Physiologically-Based Pharmacokinetic Modeling

    Applying a Global Sensitivity Analysis Workflow to Improve the Computational Efficiencies in Physiologically-Based Pharmacokinetic Modeling by Nan-Hung Hsieh, Brad Reisfeld, Frederic Y. Bois, Weihsueh A. Chiu

    Published 2018
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  4. 4
    Applications of the Cholesterol Metabolite, 4β-Hydroxycholesterol, as a Sensitive Endogenous Biomarker for Hepatic CYP3A Activity Evaluated within a PBPK Framework

    Applications of the Cholesterol Metabolite, 4β-Hydroxycholesterol, as a Sensitive Endogenous Biomarker for Hepatic CYP3A Activity Evaluated within a PBPK Framework by Aneesh V. Karkhanis, Matthew D. Harwood, Felix Stader, Frederic Y. Bois, Sibylle Neuhoff

    Published 2024
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  5. 5
    Understanding Discordance between In Vitro Dissolution, Local Gut and Systemic Bioequivalence of Budesonide in Healthy and Crohn's Disease Patients through PBPK Modeling

    Understanding Discordance between In Vitro Dissolution, Local Gut and Systemic Bioequivalence of Budesonide in Healthy and Crohn's Disease Patients through PBPK Modeling by Chunyan Han, Tiancheng Sun, Siri Kalyan Chirumamilla, Frederic Y. Bois, Mandy Xu, Amin Rostami-Hodjegan

    Published 2023
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  6. 6
    SimRFlow: An R-based workflow for automated high-throughput PBPK simulation with the Simcyp® simulator

    SimRFlow: An R-based workflow for automated high-throughput PBPK simulation with the Simcyp® simulator by Hiba Khalidi, Anthonia Onasanwo, Barira Islam, Heeseung Jo, Ciarán Fisher, Rich Aidley, Iain Gardner, Frederic Y. Bois

    Published 2022
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  7. 7
    Population PBPK modeling using parametric and nonparametric methods of the Simcyp Simulator, and Bayesian samplers

    Population PBPK modeling using parametric and nonparametric methods of the Simcyp Simulator, and Bayesian samplers by Janak R. Wedagedera, Anthonia Afuape, Siri Kalyan Chirumamilla, Hiroshi Momiji, Robert Leary, Mike Dunlavey, Richard Matthews, Khaled Abduljalil, Masoud Jamei, Frederic Y. Bois

    Published 2022
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  8. 8
    A guide to developing population files for physiologically‐based pharmacokinetic modeling in the Simcyp Simulator

    A guide to developing population files for physiologically‐based pharmacokinetic modeling in the Simcyp Simulator by Liam Curry, Sarah Alrubia, Frederic Y. Bois, Ruth Clayton, Eman El‐Khateeb, Trevor N. Johnson, Muhammad Faisal, Sibylle Neuhoff, Kris Wragg, Amin Rostami‐Hodjegan

    Published 2024
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