Zoekresultaten - Frederic Y. Bois

A Bayesian framework for virtual comparative trials and bioequivalence assessments door Frederic Y. Bois, Céline Brochot

Connect to this object online.

Opening a debate on open‐source modeling tools: Pouring fuel on fire versus extinguishing the flare of a healthy debate door Amin Rostami‐Hodjegan, Frederic Y. Bois

Connect to this object online.

Applying a Global Sensitivity Analysis Workflow to Improve the Computational Efficiencies in Physiologically-Based Pharmacokinetic Modeling door Nan-Hung Hsieh, Brad Reisfeld, Frederic Y. Bois, Weihsueh A. Chiu

Connect to this object online.

Applications of the Cholesterol Metabolite, 4β-Hydroxycholesterol, as a Sensitive Endogenous Biomarker for Hepatic CYP3A Activity Evaluated within a PBPK Framework door Aneesh V. Karkhanis, Matthew D. Harwood, Felix Stader, Frederic Y. Bois, Sibylle Neuhoff

Connect to this object online.

Understanding Discordance between In Vitro Dissolution, Local Gut and Systemic Bioequivalence of Budesonide in Healthy and Crohn's Disease Patients through PBPK Modeling door Chunyan Han, Tiancheng Sun, Siri Kalyan Chirumamilla, Frederic Y. Bois, Mandy Xu, Amin Rostami-Hodjegan

Connect to this object online.

SimRFlow: An R-based workflow for automated high-throughput PBPK simulation with the Simcyp® simulator door Hiba Khalidi, Anthonia Onasanwo, Barira Islam, Heeseung Jo, Ciarán Fisher, Rich Aidley, Iain Gardner, Frederic Y. Bois

Connect to this object online.

Population PBPK modeling using parametric and nonparametric methods of the Simcyp Simulator, and Bayesian samplers door Janak R. Wedagedera, Anthonia Afuape, Siri Kalyan Chirumamilla, Hiroshi Momiji, Robert Leary, Mike Dunlavey, Richard Matthews, Khaled Abduljalil, Masoud Jamei, Frederic Y. Bois

Connect to this object online.

A guide to developing population files for physiologically‐based pharmacokinetic modeling in the Simcyp Simulator door Liam Curry, Sarah Alrubia, Frederic Y. Bois, Ruth Clayton, Eman El‐Khateeb, Trevor N. Johnson, Muhammad Faisal, Sibylle Neuhoff, Kris Wragg, Amin Rostami‐Hodjegan

Connect to this object online.