Showing 1 - 10 results of 10 for search 'Nina Isoherranen', query time: 0.07s Refine Results
  1. 1
    Novel Mechanistic PBPK Model to Predict Renal Clearance in Varying Stages of CKD by Incorporating Tubular Adaptation and Dynamic Passive Reabsorption

    Novel Mechanistic PBPK Model to Predict Renal Clearance in Varying Stages of CKD by Incorporating Tubular Adaptation and Dynamic Passive Reabsorption by Weize Huang, Nina Isoherranen

    Published 2020
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  2. 2
    Development of a Dynamic Physiologically Based Mechanistic Kidney Model to Predict Renal Clearance

    Development of a Dynamic Physiologically Based Mechanistic Kidney Model to Predict Renal Clearance by Weize Huang, Nina Isoherranen

    Published 2018
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  3. 3
    Application of a physiologically based pharmacokinetic model to predict isoniazid disposition during pregnancy

    Application of a physiologically based pharmacokinetic model to predict isoniazid disposition during pregnancy by Ogochukwu U. Amaeze, Nina Isoherranen

    Published 2023
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  4. 4
    Predicting complex kidney drug handling using a physiologically‐based pharmacokinetic model informed by biomarker‐estimated secretory clearance and blood flow

    Predicting complex kidney drug handling using a physiologically‐based pharmacokinetic model informed by biomarker‐estimated secretory clearance and blood flow by Michael L. Granda, Weize Huang, Catherine K. Yeung, Nina Isoherranen, Bryan Kestenbaum

    Published 2024
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  5. 5
    Determinants of Cytochrome P450 2D6 mRNA Levels in Healthy Human Liver Tissue

    Determinants of Cytochrome P450 2D6 mRNA Levels in Healthy Human Liver Tissue by Miaoran Ning, Julio D. Duarte, Faith Stevison, Nina Isoherranen, Leah H. Rubin, Hyunyoung Jeong

    Published 2019
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  6. 6
    Does In Vitro Cytochrome P450 Downregulation Translate to In Vivo Drug‐Drug Interactions? Preclinical and Clinical Studies With 13‐cis‐Retinoic Acid

    Does In Vitro Cytochrome P450 Downregulation Translate to In Vivo Drug‐Drug Interactions? Preclinical and Clinical Studies With 13‐cis‐Retinoic Acid by Faith Stevison, Mika Kosaka, Jane R. Kenny, Susan Wong, Cathryn Hogarth, John K. Amory, Nina Isoherranen

    Published 2019
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  7. 7
    Altered vitamin A metabolism in human liver slices corresponds to fibrogenesis

    Altered vitamin A metabolism in human liver slices corresponds to fibrogenesis by Lindsay C. Czuba, Xia Wu, Weize Huang, Nicole Hollingshead, Jessica B. Roberto, Heidi L. Kenerson, Raymond S. Yeung, Ian N. Crispe, Nina Isoherranen

    Published 2021
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  8. 8
    Evidence of depot‐specific regulation of all‐trans‐retinoic acid biosynthesis in human adipose tissue

    Evidence of depot‐specific regulation of all‐trans‐retinoic acid biosynthesis in human adipose tissue by Katya B. Rubinow, Guo Zhong, Lindsay C. Czuba, Judy Y. Chen, Estell Williams, Zoe Parr, Saurabh Khandelwal, Daniel Kim, Jeffrey LaFrance, Nina Isoherranen

    Published 2022
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  9. 9
    Development of best practices in physiologically based pharmacokinetic modeling to support clinical pharmacology regulatory decision‐making-A workshop summary

    Development of best practices in physiologically based pharmacokinetic modeling to support clinical pharmacology regulatory decision‐making-A workshop summary by Daphney Jean, Kunal Naik, Lauren Milligan, Stephen Hall, Shiew Mei Huang, Nina Isoherranen, Colleen Kuemmel, Paul Seo, Million A. Tegenge, Yaning Wang, Yuching Yang, Xinyuan Zhang, Liang Zhao, Ping Zhao, Jessica Benjamin, Kimberly Bergman, Joseph Grillo, Rajanikanth Madabushi, Fang Wu, Hao Zhu, Issam Zineh

    Published 2021
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  10. 10
    3D cell culture models: Drug pharmacokinetics, safety assessment, and regulatory consideration

    3D cell culture models: Drug pharmacokinetics, safety assessment, and regulatory consideration by Hongbing Wang, Paul C. Brown, Edwin C.Y. Chow, Lorna Ewart, Stephen S. Ferguson, Suzanne Fitzpatrick, Benjamin S. Freedman, Grace L. Guo, William Hedrich, Scott Heyward, James Hickman, Nina Isoherranen, Albert P. Li, Qi Liu, Shannon M. Mumenthaler, James Polli, William R. Proctor, Alexandre Ribeiro, Jian‐Ying Wang, Ronald L. Wange, Shiew‐Mei Huang

    Published 2021
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